Inside America’s New Dietary Guidelines

The federal government has unveiled a sweeping overhaul of the nation’s dietary advice, signaling a sharp departure from decades of nutrition policy. Health Secretary Robert F. Kennedy Jr. announced new dietary guidelines last week that emphasize whole foods, protein, and healthy fats — while calling for a significant pullback from highly processed foods.

At a press conference, the administration introduced a newly redesigned food pyramid, one that looks nothing like its predecessors. In the new visual, red meat, cheese, vegetables, and fruits appear at the top, symbolizing foods Americans are encouraged to prioritize.

Kennedy framed the update as a historic turning point. He described the guidelines as the most significant reset of U.S. nutrition policy to date, arguing that past recommendations steered Americans toward foods that ultimately harmed public health.

“Protein and healthy fats are essential and were wrongly discouraged in prior dietary guidelines,” Kennedy said. “We are ending the war on saturated fats.”

Turning the pyramid upside down

The original food pyramid, introduced in the early 1990s, placed grains at its wide base, encouraging heavy consumption, while fats and oils sat at the narrow top. That model was retired in 2011, replaced by the “MyPlate” graphic championed by then–First Lady Michelle Obama. Now, the pyramid is back — but flipped on its head.

In an introduction to the new guidelines, Kennedy and Agriculture Secretary Brooke Rollins wrote,

We are reclaiming the food pyramid and returning it to its true purpose of educating and nourishing all Americans.

They also highlighted the health crisis driving the change, noting that more than 70% of American adults are overweight or obese. According to Kennedy and Rollins, the problem stems from a diet that has “become reliant on highly processed foods and coupled with a sedentary lifestyle.”

The guidelines call for a “dramatic reduction” in foods described as “highly processed foods laden with refined carbohydrates, added sugars, excess sodium, unhealthy fats, and chemical additives.” At the same time, they encourage diets that include meat and dairy and set limits on added sugar.

Pushback from nutrition experts

Not everyone is on board with the new approach. Some nutrition scientists argue that elevating red meat and saturated fat contradicts decades of research.

Christopher Gardner, a nutrition expert at Stanford University and a former member of the Dietary Guidelines Advisory Committee, stated:

I’m very disappointed in the new pyramid that features red meat and saturated fat sources at the very top, as if that’s something to prioritize. It does go against decades and decades of evidence and research.

Gardner favors shifting protein intake toward plant-based sources like beans rather than emphasizing animal protein.

Both the American Heart Association and the Academy of Nutrition and Dietetics also point to evidence linking excess saturated fat to heart disease.

According to NBC News, the American Heart Association said in a statement that it “commends” including several important science-based recommendations in the new guidance, including eating more fruits, vegetables and whole grains, while cutting back on added sugars and processed foods.

However, it continued,

We are concerned that recommendations regarding salt seasoning and red meat consumption could inadvertently lead consumers to exceed recommended limits for sodium and saturated fats, which are primary drivers of cardiovascular disease.

The American Medical Association (AMA) applauded the new guidance for spotlighting ultra-processed foods, added sugars and sodium, which it says fuel chronic diseases, including heart disease, diabetes and obesity.

Dr. Bobby Mukkamala, president of the AMA, said in a statement,

The Guidelines affirm that food is medicine and offer clear direction patients and physicians can use to improve health.

Marion Nestle, professor emerita of nutrition, food studies and public health at New York University, said that the advice to limit highly processed foods is a major improvement but that “everything else is weaker or has no scientific justification.” The new guidelines still retain a long-standing recommendation to limit saturated fat to 10% of daily calories. NBC News quoted Nestle’s email that states that the focus on protein…

[…] makes no sense (Americans eat plenty) other than as an excuse to advise more meat and dairy, full fat, which will make it impossible to keep saturated fat to 10% of calories or less.

Dairy takes center stage

One of the most notable changes is the elevation of cheese and other dairy products to the top of the pyramid. This shift opens the door for full-fat milk and dairy products to be offered in school meals, an idea once considered controversial.

Dariush Mozaffarian, a cardiologist, public health scientist, and director of the Food is Medicine Institute at Tufts University, said:

There’s growing evidence, based on nutrition science, that dairy foods can be beneficial… It’s pretty clear that overall milk and cheese and yogurt can be part of a healthy diet… Both low-fat and whole-fat dairy versions of milk, cheese and yogurt have been linked to lower cardiovascular risk… What’s quite interesting is that the fat content doesn’t seem to make a big difference.

Whole grains still matter, but not the refined ones

Although whole grains appear at the smallest point at the bottom of the new pyramid, the guidelines still instruct Americans to “prioritize fiber-rich whole grains.” The key difference is a sharper line drawn between whole grains and refined grains. The recommendations call for two to four servings per day of whole grains while significantly reducing refined carbohydrates such as white bread and many packaged or ready-to-eat foods.

Mozaffarian supports this part of the guidance, especially the focus on food processing. He said,

Highly processed foods are clearly harmful for a range of diseases, so to have the U.S. government recommend that a wide class of foods be eaten less because of their processing is a big deal and I think a very positive move for public health.

While the guidelines avoid the term “ultra-processed,” they repeatedly emphasize eating “real food that nourishes the body.” They also recommend no added sugar at all for children under the age of 10.

New guidance on alcohol

The updated guidelines also revise long-standing alcohol recommendations. Instead of specifying daily limits (previously up to one drink per day for women and two for men) the guidance now simply states: “Consume less alcohol for better health.”

The guidelines also clearly identify groups who should avoid alcohol entirely, including pregnant women, people recovering from alcohol use disorder, those who cannot control how much they drink, and individuals taking medications or managing medical conditions that interact with alcohol.

Although many Americans may never read the dietary guidelines themselves, their impact is far-reaching. These recommendations shape what’s served in school cafeterias, on military bases, and through federal nutrition programs for mothers and infants by setting standards for calories and nutrients.

As debate continues among scientists and health organizations, one thing is clear: The new dietary guidelines mark a bold and controversial shift in how the federal government defines healthy eating in America.

Your responses and feedback are welcome!

Source: “RFK Jr.’s new dietary guidelines go all in on meat and dairy,” NPR, 1/8/26
Source: “RFK Jr. rolls out new dietary guidelines backing more protein and full-fat dairy,” NBC News, 1/7/26
Image courtesy of USDA, used under Fair Use: Commentary

Drugs and Surgery — Reevaluation Is Inevitable

A person who lives for several decades is bound to notice something interesting, as time goes on — namely, that one generation’s scandal is the next generation’s yawn. Around the turn of the century in the USA, for instance, a decent man didn’t appear in public without a head covering; and not just any hat, but one with a hatband, a dent in the top, and a brim.

In 1900, women who initiated divorces were as rare as hen’s teeth. By the year 2000, it was quite ordinary to meet a woman who had divorced three or four husbands.

In some times and places, people are implacably set in their ways, while in others, they can’t stand to do things the same way from one week to the next. Philosophers have spoken millions of words about the human tendency to resist change, especially in instances where some members of the population are attempting to force others to act normally.

In that discussion, of course, one issue is all-important. Who is privileged to decide what is considered normal in society, as opposed to what is regarded as unacceptably deviant?

Today and us

“Who died and made you king?” is a sarcastic question that many people have good cause, several times a day, to telepathically ask a passerby some version of. More specifically, they cannot help wondering why they have to go through life hindered by the judgment of others regarding the size and condition of their bodies.

In a way, to be grossly obese is like having two heads — you just know that everybody is staring, and even if they don’t judge with hostility, they probably feel pity. So then, you spend the rest of the day mulling over the question of which is worse, hatred or contempt?

There may be nothing basically wrong, in an abstract sense, with the educational and medical establishments of society having concern about people’s health. In a general way, it is comforting to know that some of the people who run things are in charge of seeing that you don’t catch the plague or smallpox.

That is managed, in a civilized society, by having public health authorities in charge of identifying and sequestering people with a contagious disease, and convincing the healthy ones to get a shot or something, so they don’t catch the illness or spread it around. Even the most ideologically strict proponents of freedom can usually see the sense in that.

What authorities?

But when it comes to obesity, even the most convincing arguments about public responsibility for public health tend to break down. Many people feel that it is no one’s business, especially that of a government bureaucracy, to know how many pounds the scale registers when you step on it. Perhaps a valid civic-minded argument can be made for weighing a newborn baby, because at that age, weight is the most obvious characteristic that can be non-invasively measured.

But ought the authorities to care quite so much about a kindergartener’s poundage? Does the System really need to know the circumference of each 13-year-old’s waistline? Should the authorities embarrass your children at school by weighing them?

An overview

A while back, Childhood Obesity News quoted Southern California health official Jonathan Fielding:

Public health works by successive redefinition of the unacceptable.

Consider the saying, “First they ignore you, then they laugh at you, then they fight you, then you win.” Nobody is sure who first said those exact words. It is certain, however, that trade union activist Nicholas Klein expressed the same concept in different words, and many other people have, too. There was a time when nobody had ever heard of a five-day work week or a paid vacation.

But thanks to the efforts of millions of staunch labor supporters, the unacceptable was successively redefined and became the norm. A similar process occurred back when former First Lady Michelle Obama worked to warn against and prevent childhood obesity. Voices were raised against the tyranny of governmental interference in kids’ eating habits and of families’ responsibility in that area.

Still, after two presidential terms, fewer Americans were either ignoring or laughing at the concept that childhood obesity should be taken seriously. Now it appears that the same kind of gradual change might be taking place in regard to both weight-loss drugs and bariatric surgery for teens and maybe even children.

Your responses and feedback are welcome!

Image by Pat Hartman

The “W” Words

Usually, when a word is abbreviated to only its first letter, it’s a curse word. “Watchful” and “waiting” are not generally considered to be vulgar expletives, but in this context, they might as well be.

Every year, it becomes more obvious that, in the struggle against epidemic obesity, “watchful waiting” is not a strategy likely to prevail. It has become obvious that the earlier someone enters the “overweight” category, the more time they are liable to spend there. The more years a person remains overweight, the more likely they are to occupy that demographic throughout life.

Watchfulness alone is not such a bad thing. We could, in fact, use more of it — for instance, when it comes to keeping an eye on the outrageous claims made by the food industry publicists whenever they think they can get away with it. Also, it has long been felt that elementary school meals could benefit from a little more scrutiny. Maybe, without violating any basic American principles, we could still find a way to minimize the devastating effects that result from the overabundance of fast food outlets.

Some very well-informed experts tell us that 80% to 90% of childhood obesity cases persist into adulthood — even when the person makes some efforts toward positive lifestyle changes.

Apparent progress plus disappointment

There has, over the past couple of decades, been a sort of overall gold-rush tendency to take childhood obesity more seriously, characterized by flashy but soon-forgotten headlines, and sporadically causing alarm in the anti-drug and anti-surgery factions. Meanwhile, deep and interesting work goes on more quietly in the background, for instance, on an identifying characteristic called the phenotype, which is made up of the combination of influences exerted by heredity plus environment.

For instance, as Tatyana Meshcheryakova, who is one of the writers on this blog, points out, Dr. Andres Acosta describes four categories of obesity phenotypes that can guide treatment recommendations:

Hungry Gut (HG). Patients experience rapid gastric emptying and feel hungry shortly after meals.

Hungry Brain. Individuals have impaired satiety and tend to overeat during meals.

Emotional Hunger. Emotional or hedonic eating behaviors dominate.

Slow Burn. Patients have a sluggish metabolism and burn fewer calories.

As the French say, “Vive la différence!” This research team discovered that when lifestyle interventions specifically tailored for each phenotype were applied and adhered to, “patients lost more weight and had greater metabolic improvement.” Better yet, Dr. Acosta’s lab “has developed a genetic test to predict the best responders to GLP-1 RAs, showing promise in identifying individuals who might benefit most.” Here, as in so many life situations, precision targeting works better than random stabs.

There is a limit

Subtlety is overrated, so let’s go right ahead and reveal the takeaway embedded in this post. Namely, in the catalogue of human frailties, another highly overrated item is the illusion of “watchful waiting,” a dodge that all too often is a coverup for a copout. We cherish a vague notion of doing something about a situation at a certain point in time, like when summer vacation starts.

Or when school is back in session… Or when that ongoing plumbing crisis is finally solved… Or after Melissa’s birthday, when she turns 14 and we can plan a serious talk…

“Watchful waiting” is a useful technique only in a limited number of situations, and any adult who finds themselves indulging/engaging in it too often, just might be deluded. This is worth considering. Sure, get a professional opinion. But Mom or Dad, don’t kid yourself.

Don’t fall for your own propaganda. If you have noticed that Junior tends to occasionally collapse a chair into a pile of splintered wood, more than likely, others have noticed it too. Maybe even Junior, who might be confused and ashamed and wishing for some kind of help, without knowing how to ask.

Bottom line: Watchful waiting is nowhere near as useful as active intervention.

Your responses and feedback are welcome!

Source: “Unlock your unique weight loss plan,” HelloAlpha.com, undated
Image by vandesart/Pixabay

Medicare May Open the Door to Affordable Weight-Loss Drugs

Millions of older Americans could soon gain access to popular weight-loss medications at a fraction of their current cost. The Centers for Medicare and Medicaid Services (CMS) announced a new voluntary model program that would allow certain Medicare beneficiaries to obtain GLP-1 drugs for obesity for as little as $50 per month.

Under current law, Medicare is prohibited from covering medications prescribed solely for weight loss. However, both the Trump and Biden administrations have argued that obesity should be treated as a chronic disease and that GLP-1 medications play an important role in preventing serious health conditions such as diabetes, heart disease, and stroke.

The newly announced initiative, known as Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth (BALANCE), is designed to expand access to GLP-1 drugs while keeping costs under control. CMS has negotiated discounted prices with drugmakers Eli Lilly and Novo Nordisk, pairing medication access with lifestyle and nutrition support through Medicare Part D plans.

CMS Administrator Dr. Mehmet Oz said the effort is intended to “democratize access to weight-loss medication” that has previously been out of reach for many Americans. The program aims to combine medical innovation with healthier living strategies in a way that benefits patients while limiting costs for taxpayers.

How the program would work

CMS plans to negotiate both pricing and eligibility standards with drug manufacturers. Under the agreement announced last month, eligible Medicare enrollees would pay $50 per month for certain GLP-1 medications approved for obesity and diabetes, while Medicare would cover an additional $245 per prescription.

Eligibility would be limited. Those who qualify include people who are overweight with prediabetes, individuals who have experienced a stroke or other cardiovascular events, and patients with obesity combined with diabetes or severe, uncontrolled high blood pressure. Officials estimate that roughly 10% of Medicare beneficiaries would meet the criteria.

Participation in the BALANCE model is voluntary for drug manufacturers, state Medicaid programs, and Medicare Part D insurers. State Medicaid agencies can opt in starting in May 2026, with Part D plans following in January 2027. In the meantime, CMS plans to launch a short-term demonstration program that could allow Medicare beneficiaries to access GLP-1 medications as early as July. That temporary program would run through December 2031.

A shift from previous policy debates

Last year, the Biden administration proposed reinterpreting Medicare law to allow obesity drugs to be covered as treatment for a chronic condition, an approach estimated to cost Medicare $25 billion over 10 years. That effort was paused earlier this year. The current plan, by contrast, includes negotiated price reductions, which the Trump administration says will make the expansion cost-neutral.

The agreement also extends to Medicaid. Eli Lilly and Novo Nordisk have committed to offering GLP-1 medications at lower prices to state Medicaid programs, although coverage decisions will depend on individual state negotiations. As of October, 16 state Medicaid programs covered GLP-1 drugs for obesity. However, several states, including North Carolina and Michigan, have recently scaled back coverage due to rising costs.

Industry and insurer reactions

Some insurers are cautiously optimistic. The Alliance of Community Health Plans noted that GLP-1 drugs have been shown to improve health outcomes, but also warned that side effects can cause many patients to discontinue treatment within the first year. The group said it is seeking more clarity on insurer costs and long-term sustainability.

With more than 70% of U.S. adults classified as overweight or obese, CMS argues that expanding access to effective treatments could significantly reduce the burden of chronic disease nationwide. Whether the BALANCE model succeeds may depend on how well it balances affordability, patient adherence, and long-term health outcomes.

Your responses and feedback are welcome!

Source: “Medicare opens door to covering blockbuster drugs for weight loss,” CNN.com, 12/23/25
Source: “US health agency unveils weight-loss drug coverage model,” Reuters, 12/24/25
Image by RDNE Stock project/Pexels

What Does It Take to Change?

Opinions have been quietly changing about two possible treatments for childhood obesity that, up until recently, have pretty much been viewed as undesirable, and even dreaded. The most volatile reputation belongs to medication, specifically to the glucagon-like peptide-1 receptor agonists, also known as GLP-1 RAs. With this particular type of drug, it seems that the biggest percentage of conversation centers on two demographics: menopausal women and teens of either sex.

So far, the risks for teens seem mostly financial, promising to lock them into a lifelong “deal with the devil” whose hefty price will no doubt become increasingly unaffordable. Pharmaceutical products are not famous for any tendency to become less costly over time. Federal aid for medical expenses is drying up fast. Still, more parents will choose to spring for the GLP-1 subscriptions, even if it means raiding the college fund.

Inevitably, additional cases will go on record showing that these drugs can cause problems that are presently unclear or unsuspected. Even someone who is not the wagering sort can confidently bet on that.

And then, the knife

At some point, this will probably lead to an increase in the other dreaded outcome, bariatric surgery for teens, and even for children. Following that, history is expected to repeat itself and reveal still more reasons why the surgical option can also cause regrettable yet unfixable lifelong difficulties. We already know enough about that subject to be quite wary. Still, some doctors and parents will inevitably choose surgery as a prospect less odious than other possible grim outcomes.

What sort of problem could occur?

As previously discussed, harmful eating habits might result from our own past emotional upsets and psychological traumas. Registered dietitian and nutritionist Carly Zimmer reminds parents that good eating habits need support from the environment, and alerts us to some of the signs that this area has developed problems.

She teaches that weight loss medication is only a partial answer, because it either must continue throughout life, or else the subject needs to develop an entire brand new repertoire of habits around food and eating. Sadly, the most elemental fact about life is that it can change. A person may not always have the means to procure the GLP-1 meds.

An audacious proposal

In any case, the probability is strong that some day, the consumer will need to learn to live without the drug… so why not start now? If it is just a matter of developing new habits, why do people have such a hard time with the concept and the execution? The mind might recognize that change needs to take place, but how does this translate into action? If it is a mental/emotional health issue, how do we address that?

(To be continued…)

Your responses and feedback are welcome!

Image by geralt/Pixabay

Goodbye to 2025, and Try This

The facetious advice in the picture on this page has been seen millions of times online and is impossible to trace back to its source. But let’s lift a glass of sugar-free fizzy soda and drink to the health of its author. Yes, going forward into the new year, humans will continue to fight against our own best interests. Sooner or later (perhaps in 2026!) more of us will come to see the truth of another anonymous quotation:

You can fool some of the people all of the time, and fool all of the people some of the time, but — ultimately, eventually, inevitably — you can’t fool yourself.

This blog has pointed out many of the societal costs of obesity, so for the end of December, it gathers a little bouquet of talking points from the past year and the past few years, and some things to look out for in the coming months.

There are problems we don’t want to see our kids, or any kids, have to face in the upcoming year or any year subsequent to this one. In other words, let’s poke and prod ourselves to do something about looming obstacles and stop putting off the unpleasant tasks. To stall is to invite consequences that quickly outgrow the unpleasant stage and morph into real-life nightmares.

Interview with an expert

“Watchful Waiting Not Recommended For Childhood Obesity” is the title of a very recent piece by Tim Ditman, and let’s have a peek at what the expert he interviews has to say about the subject.

The American Academy of Pediatrics (AAP) has been taking a second look at some of its guidelines and softening its attitude toward surgery and medication. Some parents became nervous about venturing beyond the traditional guardrails of diet and exercise, and this is understandable.

Too often in life, the urge to “Do something!” becomes diverted or misapplied. The only thing worse than neglecting a problem is approaching it with the wrong tool. Maybe the error even lies in the mental construct of attack. Maybe “address” or “examine” is a better approach. So we do not want to start out with a misstep. When aiming for a compass bearing, even a single degree of error can lead to far, far from the intended destination.

One thing is for sure:

The AAP says waiting and hoping things get better is not a good choice.

Up until about age 12, sure, stick with the traditional methods, but beyond that age, “diet plus exercise” is not a sufficient prescription. The AAP is talking about, among other remedies, “in-person, family-based behavioral health treatment” for three months to a year. After passing that 12-year mark, the organization says, let’s start thinking about a pharmaceutical approach; and after the 13th birthday, in many cases surgery should not be arbitrarily ruled out.

Registered dietitian-nutritionist Carly Zimmer feels empathy for the difficulties that children face. Their lives are saturated with “activity” that involves mainly sitting on their ever-enlarging behinds, watching screens that glorify and strenuously recommend eating all the wrong stuff, and plenty of it. Yet and still, very often the food is not the enemy — the mind is.

Zimmer says,

Often our eating habits stem from events in our past, trauma or emotions. A mental health professional can dive into those topics and help establish a healthy relationship with food.

This is what needs to happen, not an eternal relationship with weight-loss meds acting as a band-aid, because a band-aid is glued to a person only to be replaced. That is why they are sold by the package. Commitment to a lifetime of regular injections of a very expensive drug is not a solution; not a win or a cure, or any other positive description of an outcome. It is a very poor alternative to what is ultimately possible, and many professionals are deeply committed to never settling for less.

Zimmer offers suggestions which, yes, have been heard before. That isn’t the point. If a concept has value, it is worth hearing a thousand times — until someone whose health hangs in the balance actually absorbs it. For parents, Zimmer suggests a technique that begins by adding, not subtracting. Go ahead and give the kid the same old cereal for breakfast, but offer fresh fruit, too. Maybe at some point, this particular individual will become more interested in the fruit and abandon the cereal.

Be the grownups

Get used to the idea that sometimes a child will be hungrier than other times, and don’t make a big thing out of it if they occasionally consume what you think is too much or too little. And forget that tired old “Join the clean plate club!” nonsense. Please do not set a heap of food in front of a kid. Let them start with a small serving of the fattening stuff, and maybe they will surprise you by scarfing down all the green beans.

Don’t let yourself be discouraged. You can place the same food in front of a child 20 times, only to see it scorned; and then, one day, they will eat it. When the child eventually caves and admits the stuff isn’t so bad after all, refrain from sarcasm. And now, Zimmer gives advice worth gold: “Don’t make exercise a chore.”

Parents, if there is some physical, active, calorie-burning activity your child enjoys, embrace it. Please. Find where the kid can go skateboarding or swimming, or learn gymnastics or Jiu-Jitsu, or whatever sort of exercise they can get behind. Please give them a chance to try an activity before committing to it. Make the time, find the money (it will probably not cost as much, ultimately, as weight-loss drugs or surgery), and figure out how to retain this as a major part of life, for as long as the child is into it. The rewards will be vast.

Your responses and feedback are welcome!

Source: “Watchful Waiting Not Recommended For Childhood Obesity,” RiverBender.com, 10/13/25
Image by JillWellington/Pixabay

FDA Approves Wegovy Pill

The landscape of medical weight loss just had one major change. On Monday, the Food and Drug Administration (FDA) approved a pill version of Wegovy, Novo Nordisk’s blockbuster GLP-1 weight loss drug, making it the first oral GLP-1 medication approved specifically for weight loss.

Until now, GLP-1 drugs such as semaglutide (found in Ozempic and Wegovy) and tirzepatide (used in Mounjaro and Zepbound) have only been available as injections. While highly effective, injections can be a barrier for many patients. The arrival of a daily pill could change that.

Novo Nordisk expects the Wegovy pill to be widely available in January, according to a company spokesperson. A competing oral GLP-1 pill from Eli Lilly is also expected to gain FDA approval in the coming months.

Why the Wegovy pill matters

GLP-1 drugs were initially developed to treat type 2 diabetes, but they quickly gained attention for their ability to drive significant weight loss. Their popularity has soared in recent years as obesity treatment has shifted toward more effective medical options.

Dr. Christopher McGowan, a gastroenterologist who runs a weight loss clinic in Cary, North Carolina, told NBC News:

This is a meaningful step forward in the field… It won’t replace injectables, but it broadens our tool kit in an important way.

Dr. McGowan emphasized that the form of the medication itself may help more people feel comfortable starting treatment:

Pills are familiar, nonintimidating and fit more naturally into most people’s routines… For many patients, a pill isn’t just easier, it’s psychologically more acceptable.

Novo Nordisk already sells an oral version of semaglutide called Rybelsus for diabetes, but it comes in a lower dose. The newly approved Wegovy pill is formulated specifically for weight loss, and at higher doses.

Cost, coverage, and access questions

Novo Nordisk has not yet released the list price for the Wegovy pill, which must be taken daily, but it is expected to cost less than the weekly injections. Insurance coverage, however, remains uncertain. Many private insurers restrict coverage of injectable weight loss drugs because of their high cost.

Medicare is legally barred from covering medications approved solely for weight loss. However, the Wegovy pill was also approved for lowering heart disease risk, which Medicare does cover — potentially opening the door for broader access.

In November, Novo Nordisk reached an agreement with the Trump administration to sell the lowest dose of the pill for $149 per month for people paying out of pocket, in exchange for tariff relief. Eli Lilly made a similar deal for its own weight loss pill.

How effective is the Wegovy pill?

Clinical trial data suggest the pill works nearly as well as the injectable version — if taken correctly. Phase 3 trial results published in The New England Journal of Medicine showed that participants taking the highest dose of the Wegovy pill lost an average of 16.6% of their body weight after 64 weeks. By comparison, those in the placebo group lost just 2.2%. That result is roughly on par with injectable Wegovy, which reduced weight by about 15% after 68 weeks in earlier trials.

However, adherence may be a major challenge. Dr. Shauna Levy, medical director of the Tulane Weight Loss Center, noted that the pill must be taken first thing in the morning, on an empty stomach, with no more than four ounces of water. Participants who failed to follow the strict schedule lost less weight, about 13.6% of their body weight on average.

The key uncertainty is how patients will do outside of clinical trials. The open question is “real-world performance,” Dr. McGowan said. “Will patients tolerate the daily dosing and strict timing? Will they stay on long enough to see meaningful results? We don’t know yet.”

Side effects and comparisons to injections

Like injectable GLP-1 drugs, the most common side effects reported with the Wegovy pill were gastrointestinal, including nausea and vomiting. In some cases, those effects may be stronger.

Dr. McGowan explained that side effects from the pill version can feel “more intense” because the medication reaches the stomach all at once. “The challenges we see with injectable GLP-1s don’t magically disappear with a tablet,” he said.

While the Wegovy pill delivers weight loss comparable to injectable Wegovy, newer injectable drugs still lead the field. Lilly’s Zepbound helped patients lose 22.5% of their body weight after 72 weeks in clinical trials, and its next-generation injection, retatrutide, produced average weight loss of 24% after just 48 weeks.

Novo Nordisk says the differences may come down to how the medication is absorbed. Because pills are broken down in the digestive tract, less of the drug reaches the bloodstream compared to injections. To compensate, the Wegovy pill is taken daily and at higher doses.

The pill’s effectiveness is closer to Lilly’s oral drug orforglipron, which led to about 10.5% weight loss after 72 weeks in late-stage trials. These figures, however, are not from direct head-to-head comparisons.

Avoiding past shortages

When injectable Wegovy first launched, it was plagued by prolonged shortages. This time, Novo Nordisk says it has increased pill production ahead of the rollout. Another consideration is that oral medications are often easier to manufacture than injectables, which could help prevent supply issues and improve access.

For now, the Wegovy pill represents a promising new chapter in the rapidly evolving science of weight loss treatment.

Your responses and feedback are welcome!

Source: “FDA approves Novo Nordisk’s Wegovy pill, the first and only oral GLP-1 for weight loss in adults,” PR Newswire, 12/22/25
Source: “FDA approves Wegovy weight loss pill from Novo Nordisk,” NBC News, 12/22/25
Image by JESHOOTS.com/Pexels

Additional Complicated Angles of Weight

All the behaviors that combine to define an eating disorder are just maladaptive coping strategies, writes Brittney Williams of Fairhaven Treatment Center. According to Internal Family Systems (IFS) theory, the inner “exiles” who perform those behaviors do not need to be banished, only freed of their painful burdens:

The goal of coming to see eating disorders as a “part” similar to the rest of an individual’s various “parts” gives a chance for them to be seen, heard, understood, and transformed.

In other words, the concept here is to own the eating disorder and the ghostly entities that inhabit you, because to admit in the first place that they exist is the only way to tame them.

“Parts work,” as pioneered by Dr. Richard Schwartz, is claimed to be effective not only with eating issues but with “many mental disorders.” According to this worldview, for a person to contain several beings is not a pathology but the natural order of things. Rather than suffer banishment, the multiple entities within should all be consulted and regarded, because if given the chance, they can and will prove helpful. In other words,

The foundation of this model offers a beneficial framework for clinicians to approach clients’ eating disorder behavior from an internal relational perspective rather than as maladaptive behaviors.

To shun the “parts” only nudges them into extreme “look at me” behavior, so it is much more helpful to grant them respectful attention. Trying to ignore them will not accomplish anything anyway, so you might as well give them a chance to be heard. The “parts” all want to help, and they are not going anywhere, so the smart thing to do is get to know them and understand what they bring to the table.

The downside

This all sounds very inspiring, but apparently it can go plenty wrong. Often, good intentions are not enough. IFS is sometimes paired with intuitive eating, “a non-diet approach to food intake that involves listening to your body’s hunger and satiety cues and eating accordingly… [Y]ou can eat what you want and when you want, as long as you are tuning into your body’s signals.”

Success depends on interoception, “the ability to perceive physical sensations that arise from within your body. Intuitive eating relies on interoception since you must be attuned to your hunger and fullness in order to give your body the fuel it needs.” It is all too easy to imagine how readily this philosophy could jump the track.

In one way, the IFS worldview is very positive, in assuming that your healthy self is tucked away in there somewhere — you just have to locate and connect with it. But matters are not always quite so simple. In group therapy, listening to the wrong person can be a problem. Artificial Intelligence entities, no matter how cleverly created, can be wrong. The “parts” of a person, the “managers” and “firefighters” who are meant to fix things, can be mistaken. They can give bad and even dangerous advice.

One aspect of relatability is in the bag already. Thanks to technology, AI can be engineered to speak in a voice so convincing that perfectly sane people are swindled into sending their life savings to bail their grandchildren out of jail.

So, why shouldn’t an equally convincing fake entity succeed in helping a person feel worthy and capable of making enormous life changes and losing 100 pounds? Or, if the human in need of therapy is a child, wouldn’t it be theoretically possible to dispose of breath and heartbeat entirely, and let AI help the kids adopt, painlessly, a lifestyle through which they would never become overweight in the first place?

Caution is advised

With self-protective clarity, a young teen in therapy might recognize that he or she has an absolutely terrible parent. (If they didn’t already know it.) Still, the knowledge does not imply a recommendation to murder that parent. This is where professionals really must possess skill, in the realm of helping patients transform pain and anger into positive outcomes. Sadly, that result is not always achieved.

How bad can it be? Of course, a response that triggers binge eating is apt to have quite different results from a response that triggers homicidal tendencies. Does a therapist ever fear setting off a murder or a suicide? Even worse, intentional harm of this kind has been done on purpose.

According to investigators, government agencies in the Sixties were involved in influencing some very bad people to become even worse, and earn public disapproval that would have political consequences. Basically, there is good brainwashing and bad brainwashing, and caution is advisable.

IFS has run into some trouble in this area. As its popularity grew, some families were inevitably shattered when false memories convinced patients that their parents had abused or tried to kill them. Rachel Corbett wrote about this in detail, explaining that thorough and comprehensive training is vital, especially when dealing with vulnerable people who are at a life juncture when they really could use some family support.

Your responses and feedback are welcome!

Source: “The IFS Model With Eating Disorders: ED is Just a Part of You,” EatingDisorderHope.com, 10/11/23
Source: “Eating Disorders and the Internal Family Systems Model,” EatingDisorderHope.com, 10/19/20
Source: “Using internal family systems with intuitive eating to enhance eating disorder recovery,” WithinHealth.com, undated
Source: “Grandparent Scams Take Advantage of Your Love for Your Family,” AARP.org, 02/13/25
Source: “The Therapy That Can Break You,” TheCut.com, 10/30/25
Image by GDJ/Pixabay

Some Complicated Angles of Weight

Although styles of therapy differ, it is widely accepted that the root of all psychological malfunction is pain. In the animal kingdom, the amoeba is about as simple a creature as can be. And yet, even the humble amoeba knows to avoid pain, and somehow recognizes the appropriate moment to flee from a molecule of poison.

In that respect, people are very much like amoebae, but have more freedom of choice in their reactions. Amoebae probably can’t even fight. Their choice of displacement activity is quite limited.

Now, what about the entities that facilitate the healing of pain? Psychologists, for instance — do they absolutely need to be human?

As we have discussed, one aspect of psychological therapy has developed quite rapidly and noticeably into an overwhelming issue. Can excellent results be achieved with less, or even zero, human interaction? Can human connection be adapted and reconceptualized into something equally curative, by perfecting the ability of Artificial Intellligence to imitate high-quality connection?

It’s not that surprising

One might ask, why shouldn’t this be the case? Look, for instance, at books. They are made from common materials, and from symbols that are very different from human speech or breath. Furthermore, vast numbers of humans have been and still are unable to read books — and yet the influence that books have exerted on many of us (for better or worse) throughout the ages is a true marvel.

An important aspect of convincing relatability is in the bag already. Thanks to technology, AI can be engineered to swindle people out of their life savings by speaking in a voice so relatable that a perfectly sane adult will think it’s their grandkid, in desperate need of bail money. Compared to such an accomplishment, the ability to sound like the world’s most empathic therapist is no big deal.

One thought leads inevitably to another

So, why shouldn’t an equally convincing fake entity succeed in helping a person feel worthy and capable of making enormous life changes and losing 100 pounds? Or, if the human in need of therapy is a child wouldn’t it be theoretically possible to dispose of breath and heartbeat entirely, and let AI help the kids adopt, painlessly, a lifestyle through which they would never become overweight in the first place?

How much actual personal contact between patient and therapist is actually optimal? Can a group of other people with similar problems serve the personal-connection need just as well?

Maybe so. Millions of group therapy participants will attest that to go through the self-discovery experience with a cohort of similarly affected others can be incredibly helpful. For many, it has been vital to associate with others who are on the same basic journey, but a little bit ahead.

As Alcoholics Anonymous and similar groups have demonstrated, we also benefit from hanging out with people who travel a little way behind us so we can take our well-deserved turn as experienced encouragers of others on the same path.

(To be continued…)

Image by dbutlerdidit/Pixabay

New Gut Research for Obesity and Diabetes

Scientists have long suspected that the trillions of microbes living in our gut do more than help digest food. Now, new research suggests they may play a direct role in shaping how our bodies handle sugar and fat — key factors in obesity and type 2 diabetes.

A recent study conducted at Harvard University, with support from Brazil’s São Paulo Research Foundation (FAPESP), has uncovered a network of small molecules produced by gut microbes that travel from the intestine to the liver and then throughout the body. These compounds, known as metabolites, appear to influence how the liver processes energy and how sensitive the body is to insulin. The findings were published in the journal Cell Metabolism and could open the door to new ways of treating metabolic disease.

The gut–liver highway

To understand the discovery, it helps to know how blood flows through the body. Much of the blood leaving the intestine doesn’t go straight into the general circulation. Instead, it travels through a special vessel called the hepatic portal vein, which delivers nutrients and microbial byproducts directly to the liver first.

“The liver is essentially the first organ to see what’s coming from the gut,” explains lead author Vitor Rosetto Muñoz, a postdoctoral researcher at the University of São Paulo who conducted part of the study at Harvard’s Joslin Diabetes Center. Once these gut-derived compounds reach the liver, they can be modified, broken down, or released into the bloodstream to affect other organs.

By comparing blood from the hepatic portal vein with blood circulating throughout the rest of the body, the researchers were able to pinpoint which metabolites come from the gut and how they may influence metabolism along the way.

Why the gut microbiome matters

In recent years, researchers have learned that people with obesity, insulin resistance, or type 2 diabetes often have a different mix of gut bacteria than people without these conditions. What’s been harder to determine is exactly how those microbes affect metabolism.

To explore this, the team studied mice with different genetic risks for obesity and diabetes. They analyzed metabolites in both portal vein blood and peripheral blood, offering a clearer picture of what the liver is exposed to right after digestion.

In healthy mice, researchers identified more than 100 metabolites enriched in blood traveling from the gut to the liver. But in mice genetically prone to obesity and diabetes (and fed a high-fat diet), that number dropped dramatically. This suggests that diet and genetics together can reshape the chemical messages sent from the gut to the liver.

Interestingly, mice that were naturally resistant to metabolic disease showed a different metabolite pattern altogether. This points to a complex interaction between a person’s genes, their environment, and their gut microbiome.

Disrupting the microbiome changes metabolism

To test whether gut bacteria were truly responsible for these changes, researchers treated some mice with antibiotics that altered their gut microbiome. As expected, this disrupted microbial populations and also shifted the types of metabolites found in the blood.

One metabolite that increased stood out: mesaconate, a compound involved in the Krebs cycle, which is the process cells use to generate energy. When scientists exposed liver cells to mesaconate and related molecules in the lab, they saw improvements in insulin signaling. The compounds also helped regulate genes linked to fat buildup and fat burning in the liver — two processes that are often impaired in metabolic disease.

These findings suggest that certain gut-derived metabolites can directly improve liver metabolism, even in the context of a high-fat diet.

What this could mean for the future

While this research was done in mice, it provides a detailed map of how gut microbes may influence metabolic health through the liver. The next step is to better understand how each metabolite is produced and how it behaves in the body.

Over time, this work could help scientists identify specific microbial byproducts that might be used as treatments—or inspire therapies that reshape the gut microbiome to improve insulin sensitivity and reduce the risk of obesity and type 2 diabetes.

So, remember: What happens in your gut doesn’t stay in your gut. It may travel straight to your liver and shape your metabolic health in powerful ways!

Your responses and feedback are welcome!

Source: “Harvard gut discovery could change how we treat obesity and diabetes,” ScienceDaily, 12/14/25
Source: “Metabolites produced in the intestine play a central role in controlling obesity and diabetes,” Agencia.fapesp.br, 11/26/25
Source: “Portal vein-enriched metabolites as intermediate regulators of the gut microbiome in insulin resistance,” ScienceDirect, 10/7/25
Image by Wassily Kandark/Pexels

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Profiles: Kids Struggling with Weight

Profiles: Kids Struggling with Obesity top bottom

The Book

OVERWEIGHT: What Kids Say explores the obesity problem from the often-overlooked perspective of children struggling with being overweight.

About Dr. Robert A. Pretlow

Dr. Robert A. Pretlow is a pediatrician and childhood obesity specialist. He has been researching and spreading awareness on the childhood obesity epidemic in the US for more than a decade.
You can contact Dr. Pretlow at:

Presentations

Dr. Pretlow’s invited presentation at the American Society of Animal Science 2020 Conference
What’s Causing Obesity in Companion Animals and What Can We Do About It

Dr. Pretlow’s invited presentation at the World Obesity Federation 2019 Conference:
Food/Eating Addiction and the Displacement Mechanism

Dr. Pretlow’s Multi-Center Clinical Trial Kick-off Speech 2018:
Obesity: Tackling the Root Cause

Dr. Pretlow’s 2017 Workshop on
Treatment of Obesity Using the Addiction Model

Dr. Pretlow’s invited presentation for
TEC and UNC 2016

Dr. Pretlow’s invited presentation at the 2015 Obesity Summit in London, UK.

Dr. Pretlow’s invited keynote at the 2014 European Childhood Obesity Group Congress in Salzburg, Austria.

Dr. Pretlow’s presentation at the 2013 European Congress on Obesity in Liverpool, UK.

Dr. Pretlow’s presentation at the 2011 International Conference on Childhood Obesity in Lisbon, Portugal.

Dr. Pretlow’s presentation at the 2010 Uniting Against Childhood Obesity Conference in Houston, TX.