Cherished Belief Bites the Dust — Or Not

Bats are blind; seeing red infuriates a bull; freezing prolongs battery life; rice can dry out a wet cell phone? No way.

When Columbus set sail, people believed the Earth was flat, and the Jonestown Massacre victims were killed by poisoned Kool-Aid. Nope.

Does marijuana cause users to “get the munchies” and consequently grow obese? It ain’t necessarily so, because grass “could actually have surprising effects on your waistline,” as Lester Black recently reported for SFGATE.

This news emerged from work done at the University of California, Riverside. The subjects of these experiments were not humans, but mice, whose metabolisms were remarkably affected by ingesting concentrated cannabis oil, with results that included weight loss.

Say whut?

Prof. Nicholas DiPatrizio led a team in tinkering with molecules, as researchers will often do in efforts to bend nature to our will. They obtained results that encouraged them to believe this is only the beginning of a totally unexpected series of beneficial discoveries.

At first, this all sounds as heretical as believing that the sun rises in the west. Everyone knows the correct answer is east.

But it only rises in the east because humans decided to give that name to the sunrise side of the sky. If we had named it “west” instead, that is where the sun would absolutely rise.

Only, it doesn’t rise at all. That is only another myth, one that was eventually debunked when people finally figured that the sun stays in relatively the same place, while the Earth actually revolves. In defining scientific truth, many factors are involved.

Anyway, the scholars obtained some obese mice and divided them into two teams. Some were fed an isolated form of THC, while others received cannabis oil containing “a broad spectrum of cannabis compounds.”

Head to head

Both teams lost some weight, but “the outcomes differed noticeably on other metabolic functions.” The THC mice “still had impaired metabolic function that mirrored diabetes.” The cannabis oil mice “saw their metabolic function return to normal.”

Obviously, much work remains to be done, but the expectation exists that “targeting this widespread system could unlock new therapies.” Some products are already on the market, resulting from earlier work done by other researchers. For example,

Tetrahydrocannabivarin, a natural cannabis compound shortened to THCV, has been shown to cause reduced appetite and increased stimulation.

Of course, Dr. DiPatrizio’s team specifies, just because a new discovery looks promising when tested on animals, there are no guarantees about eventual human benefit. No guarantees, but plenty of hope that obesity and/or diabetes in humans will eventually be defeated by new discoveries. Meanwhile, the scientists involved in the quest are feeling the intoxication that may match or exceed any sensation available from cannabis.

Are they a bunch of deluded hallucinators? Not hardly! According to a recent Cleveland Clinic page, medical marijuana is already in use for more than 20 medical conditions, including Alzheimer’s disease, cancer, fibromyalgia, multiple sclerosis, glaucoma, Tourette syndrome, intractable pain, and the list goes on.

Many questions remain about why cannabinoids can do what they do, and also why different people react in unexpected ways. Factors include age, genetic predisposition, gender, dosage, method of consumption, possible conflict with other meds, and more.

But the verdict so far is that the gains outweigh the difficulties. Another problem, of course, is getting the law on the appropriate side of any issues that are involved.

Your responses and feedback are welcome!

Source: “15 Common Science Myths and Misconceptions — Busted,” RD.com, undated
Source: “13 Widely Believed History Myths,” BuzzFeed.com, 3/23/26
Source: “New Calif. study finds evidence cannabis could treat obesity, diabetes,” SFGATE.com, 05/14/26
Image by Erin Hinterland/Pixabay

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Profiles: Kids Struggling with Weight

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OVERWEIGHT: What Kids Say explores the obesity problem from the often-overlooked perspective of children struggling with being overweight.

About Dr. Robert A. Pretlow

Dr. Robert A. Pretlow is a pediatrician and childhood obesity specialist. He has been researching and spreading awareness on the childhood obesity epidemic in the US for more than a decade.
You can contact Dr. Pretlow at:

Presentations

Dr. Pretlow’s invited presentation at the American Society of Animal Science 2020 Conference
What’s Causing Obesity in Companion Animals and What Can We Do About It

Dr. Pretlow’s invited presentation at the World Obesity Federation 2019 Conference:
Food/Eating Addiction and the Displacement Mechanism

Dr. Pretlow’s Multi-Center Clinical Trial Kick-off Speech 2018:
Obesity: Tackling the Root Cause

Dr. Pretlow’s 2017 Workshop on
Treatment of Obesity Using the Addiction Model

Dr. Pretlow’s invited presentation for
TEC and UNC 2016

Dr. Pretlow’s invited presentation at the 2015 Obesity Summit in London, UK.

Dr. Pretlow’s invited keynote at the 2014 European Childhood Obesity Group Congress in Salzburg, Austria.

Dr. Pretlow’s presentation at the 2013 European Congress on Obesity in Liverpool, UK.

Dr. Pretlow’s presentation at the 2011 International Conference on Childhood Obesity in Lisbon, Portugal.

Dr. Pretlow’s presentation at the 2010 Uniting Against Childhood Obesity Conference in Houston, TX.

Food & Health Resources