More Alleged Obesity Villains

Many substances have been suspected of contributing to childhood obesity, and antacid medications are among them. A 2018 report warned that young children who are prescribed drugs meant to prevent excess stomach acid “may be at heightened risk of obesity.” Moreover, “this association strengthened for each 30-day supply prescribed.”

The possibility of a cause-and-effect relationship was based on the medical records of more than 333,000 children under two years old. Like all honest research papers, this one included caveats:

Although the largest study of its kind, it is nevertheless observational, and as such, can’t establish cause. And potentially influential information on how much the children’s mothers weighed, and whether they smoked or had other underlying conditions wasn’t available.

Another wrinkle was suggested by pediatric gastroenterology researcher Gail Cresci, Ph.D., RD, of Cleveland Clinic, who speculated that the problem might lie in interference with the microbiome:

Antacids take away the first line of the body’s defense against ingested pathogens by decreasing gastric acidity which can destroy many of these pathogens. Obesity is known to be associated with ‘low grade’ inflammation. This then may allow the pathogens to reach the distal intestine and then alter microbial diversity.

Is grilling guilty?

Another obesity villain suspect may be the food preparation method known as grilling, which is very popular in many circles.

A recent study has found that a common chemical produced by grilling foods may play a significant role in causing obesity, type 2 diabetes, and insulin resistance. This has to do with a suspected obesity risk factor known as AGEs, or advanced glycation endproducts. One of these endproducts is MG, or methylglyoxal, a compound that causes mice to “gain a significant amount of weight to their abdomens” and impairs the body’s own inflammation response. There are also carcinogenic byproducts. According to the study,

Over the four generations, the mice that were fed a diet with MG had more body fat [than the control group] and developed early insulin resistance… The abdominal fat in mice fed MG was converted into fat cells that prevented the metabolism of glucose and impeded fat turnover. This inhibited process, in turn, contributed to the development of insulin resistance and diabetes.

But like many stories, this one has two sides. An uncredited, undated piece from HealWithFood.org makes the claim that grilling has an “inherent weight loss benefit” because the fat cooks out and drips down into the grill, rather than pooling around the meat and being resorbed into it. This is said to reduce a person’s fat intake “significantly” or, according to a similar website, “dramatically.” The public is also reminded that fish and vegetables (low-fat and no-fat) can be deliciously grilled.

Your responses and feedback are welcome!

Source: “Childhood antibiotics and antacids may be linked to heightened obesity risk,” ScienceDaily.com, 10/30/18
Source: “Antibiotics, Antacids Linked to Obesity Risk in Kids,” Healthline.com, 11/11/18
Source: “Grilled Food May Lead to Obesity and Diabetes,” MedicalDaily.com, 08/21/21
Source: “Weight Loss Benefits and Other Advantages of Grilling Food,” undated, uncredited
Image by woodleywonderworks/CC BY 2.0

Obscure Purported Obesity Villains

Well over 100 substances, practices, and societal conditions have been blamed for contributing to the growth of childhood obesity. Most of the accusations are very difficult to substantiate, mainly because there are so many of them, pointing at dozens of other factors that may or may not actually have an effect.

How many of these things are not causes of obesity, but rather co-symptoms that exist along with obesity in some individuals? Morton Downey himself suggested possible reasons for confusion. Many of the separate causes could be gathered under one umbrella, like socio-economic inequality. How far down must humankind dig to get to the bottom of this?

Downey speculated on cultural, regional, ethnic, or local factors. Those factors are, of course, some of the stubbornest resisters of change. For instance, some people want to put an end to the overeating festival known as Thanksgiving. To simply insist that we give it up because it makes us fat would meet with massive resistance. But if enough people concluded that the holiday should be abandoned for moral reasons having to do with the legitimacy of the colonization of the continent, that would be a different matter.

The engines of change

In other words, sometimes, a new cultural factor outweighs the old cultural factor that previously held sway. The authorities in charge of our safety have to know what our ingrained beliefs are, in order to figure out how to change them on behalf of public health. Like it or not, the government is in the business of brainwashing people for their own good.

Childhood Obesity News has mentioned several of the more commonly held beliefs, as curated by Downey. His list (which was updated after the original 104 items) gave a reference for each theoretical cause, but that article has apparently become lost in cyberspace. So, research begins afresh.

One example

In the United States, not many people have heard of the betel nut, and even fewer are familiar with its Latin name, Areca catechu. However, thanks to the activities of some 600 million humans in the Asian-Pacific sector of the globe who habitually chew the betel nut, it is the world’s fourth most frequently used addictive substance. Aside from causing cancer of the mouth and esophagus, the betel nut is also found to cause hypertension, heart disease, kidney disease, metabolic syndrome, and type 2 diabetes.

A little bundle or parcel is made of the nut, some lime, and maybe some tobacco, wrapped in a betel leaf. Some people go through 10 of these a day. The practice is popular for the same reason as coca leaf chewing in South America. It keeps the hard-working users awake and alert, though they also find it relaxing. The habit results in horribly stained teeth and the frequent spitting of red saliva, which does seem to be culturally less acceptable than in the past.

But that is not all. According to one study’s findings,

Betel nut chewing was closely associated with BMI and it was proposed that the underlying cause was increased appetite of betel nut chewers… [Researchers] also proposed that obesity could be the possible intermediary by which betel nut chewing could increase cardiovascular disease…

Because betel nut consumption may increase the risk for obesity and its complications, it is important to assess the association between betel nut chewing and obesity in Asian countries.

Subsequent studies showed mixed results, because there are so many competing factors, among them smoking and alcohol consumption. A 2015 study carried out in the Mariana Islands (Guam and Saipan) looked at 300 betel nut chewers, slightly more than half of them male. The researchers differentiated between Class 1 hardcore users who took their betel straight, and Class 2 users who chewed it mixed with tobacco:

The findings suggest that Class 1 chewing pattern is associated with high central adiposity among males, but not among females in the Mariana Islands.

Because betel nut chewing is one of the very stubborn ingrained cultural factors about which Downey spoke, the struggle to convince people to give up this habit is real.

Your responses and feedback are welcome!

Source: “Betel Nut Chewing Is Strongly Associated With General and Central Obesity in Chinese Male Middle-aged Adults,” NIH.gov, 02/26/09
Source: “Pattern of Areca (betel) Nut Chewing and Obesity Measures in Guam and Saipan, Mariana Islands,” Academic.oup.com, 09/23/15
Image by Frank Starmer/CC BY-SA 2.0

The Absorption of Morton Downey

Morton Downey was previously mentioned by Childhood Obesity News in connection with his list of 104 different factors that have been implicated in causing obesity. In an earlier post, we touched on the “obesity villains” with more obvious and straightforward financial roots, like government policy regarding agriculture; advertising that targets children; and snack-vending machines in schools.

For several years, Downey served as executive director of the American Obesity Association, and then for two years as executive vice president of the Obesity Society. One of his successful missions was to convince the IRS that, for the purpose of filling out individual income tax forms, weight-loss treatment expenses should be deductible.

Concerning obesity, his “list of putative causes” page has disappeared from the internet, but it once included these words regarding the large number of factors that have been suggested as contributory to widespread obesity in the contemporary scene:

First, is there some problem with the research methodology that so many and diverse potential causes are identified? Second, are a number of named putative causes symptoms or manifestations of underlying, deeper causes? And what are those? Third, to what extent are identified putative causes reflections of local, regional, ethnic or cultural factors?

Downey’s point was that most of the suspected obesity villains in our lives really have very little to do with the energy balance formulation that the world has become accustomed to accepting. He suggested that there is more to obesity than the traditional calories-in, calories-out paradigm that has become so taken for granted.

The Downey Obesity Report website was acquired by another site, ObviouslyFat.com, that apparently has not made much use of Downey’s material, since his name appears only once in the entire website. But it seems to have been founded very recently, like earlier this year, so maybe more of his writings will eventually emerge.

The new site, which has a very frank fat acceptance vibe, appears to exist specifically to direct customers to obesity-oriented products, of which it has compiled quite a variety. There are guides to mobility scooters, heavy-duty stepladders, and 6XL knee braces. There is specialized patio furniture. Some of the products are very personal, like shower chairs, toilet seats and wiping aids, of which at least five different brands exist.

Others items appear quite useful for the active heavy person who needs a beach chair, hammock, kayak, surfboard, or above-ground pool ladder made to scale. Also, there are sleep aids, from heavy-duty air mattresses to a bed that can support 3,500 pounds. Apparently, there also exists a plus-size chair with convenient holders for up to six beverages.

The page that contains 15 fashion tips for men looks very useful. The main rule is to stay away from baggy clothing and go with the closer-fitting duds instead. And for heaven’s sake, choose decent shoes. Clothing and shoes of course make up a huge category, including a belly band holster touted as the “top concealed carry method for fat guys.”

Your responses and feedback are welcome!

Source: “The Putative 104 Causes of Obesity Update,” DowneyObesityReport.com, 10/22/15
Source: “Downey Obesity Report Acquisition & Merger — Find Out The Latest,” ObviouslyFat.com, 2021
Image by Tim Pierce/CC BY 2.0

What’s Up With Energy?

Inactivity or overeating? For the young, which is the bigger obesity villain? This question, in the words of journalist Gretchen Reynolds,

[…] remains murky and matters, as obesity researchers point out, because we cannot effectively respond to a health crisis unless we know its causes.

People are still talking about the research on…

[…] the lifestyles, diets and body compositions of Amazonian children who live in rural, foraging communities… The in-depth study found that the rural children, who run, play and forage for hours, are leaner and more active than their urban counterparts. But they do not burn more calories day-to-day, a surprising finding that implicates the urban children’s modernized diets in their weight gain.

The Shuar are pretty much hunter-gatherers, with some fishing and subsistence farming added to the mix. Of necessity, their diet includes starchy vegetables, which are not favored by nutritionists. And yet, it is rare for either children or adults to be overweight or to suffer from malnourishment.

The Ecuadorian kids are not the only ones concerned, since the facts are believed to “have implications for the rising rates of obesity in both children and adults worldwide.”

In a previous study, Dr. Sam Urlacher compared the Shuar children’s energy expenditure with that of some sedentary, heavy children in the USA. Turns out, the young Ecuadorians burned pretty much the same number of calories as the overweight North Americans. In the followup study, those rural Shuar children were compared to some Shuar townies, in the same age group and with the same genetic heritage.

The urban Shuar children proved to be considerably heavier than their rural counterparts. About a third were overweight by World Health Organization criteria. None of the rural children were. The urban kids also generally were more sedentary. But all of the children, rural or urban, active or not, burned about the same number of calories every day.

Study co-author Dr. Herman Pontzer of Duke University teaches evolutionary anthropology, with an emphasis on the intersection of evolution and human metabolism. Apparently, the influence goes both ways. Dr. Pontzer had also previously studied the Hadza, hunter-gatherers of Tanzania, who spent their days in moderate-to-strenuous activity while burning “about the same number of total calories daily as much-more-sedentary Westerners.” His thought is that our bodies figure out where to allocate the available energy, according to whatever we are doing with our lives. Reynolds says,

The result is that our average, daily energy expenditure remains within a narrow band of total calories, helpful for avoiding starvation among active hunter-gatherers, but disheartening for those of us in the modern world who find that more exercise does not equate to much, if any, weight loss.

She goes on to quote Dr. Urlacher:

Exercise is still very important for children, for all sorts of reasons. But keeping physical activity up may not be enough to deal with childhood obesity.

Your responses and feedback are welcome!

Source: “Exercise vs. Diet? What Children of the Amazon Can Teach Us About Weight Gain,” NYTimes.com, 02/24/21
Image by Maurizio Costanzo/CC BY 2.0

An Ounce of Prevention Is Worth a Pound of Cure

To express the thought behind yesterday’s post another way: Exercise with weight loss as your goal, and you may face disappointment. Exercise to gain dozens of contributory benefits, and for a general feeling of well-being, and you win every day.

Of course, if exercise were the answer to everything, all the time, life would be too simple. Mulling over a color-coded map embodying research from the Robert Wood Johnson Foundation, it is easy to see that in the realm of weight, other factors must be at work. Among the “Percent of adults who are physically inactive,” the most obese states are Mississippi, Oklahoma, Kentucky, Louisiana, and Alabama. It’s as if Mississippi (purple) is the epicenter, with a ring of not-quite-so-bad (red) states around it, and every one of them borders on an orange state. It really is quite visually striking, in a jagged-edged bullseye kind of way.

The blur of reality

Still, many Americans carry a stereotype in our heads about states that tend more toward the rural; a belief that they are populated by wiry farmers, mechanics, horse trainers, etc., who are at the peak of health because their everyday lives entail lots of movement. Today, the residents of those states may not even be particularly slothful, but of course, times change.

A lot of agricultural labor has been automated, so farmworkers are not necessarily doing drastic chores from dawn to dusk. Before the internal combustion engine took over, people in the country, or in semi-rural areas, used to stay fit by walking, chopping wood, and wrangling critters. But although some country folk still do hard physical labor, and get plenty of exercise, a huge number are overweight or obese. (Side note: In the face of all this, it seems paradoxical for city dwellers to blame their obesity on the “built environment.”)

Six of one, half a dozen of the other

Remember “The Bus Conductors’ Secret“? It raised the question: Do strenuous jobs make people fit, or do fit people apply for and get hired for strenuous jobs? Even the most meticulous studies can seem to contradict each other. Does living in a two-story house or an upstairs apartment increase longevity? Do out-of-shape people abandon living quarters that have stairs, or tend not to move in, in the first place? Population “epidemiology” is fraught with missing basic factors, or misinterpretation of cause and effect.

A study of children in Ecuador raised puzzling questions, which we will look at next. The only point where there is consensus is that overweight adults probably started out as overweight children. That seems to be the one truth to which we can stubbornly cling. “An ounce of prevention is worth a pound of cure.”

Your responses and feedback are welcome!

Source: “Physical Inactivity in the United States,” StateOfChildhoodObesity.org, 2019
Image by Kevan/CC BY 2.0

Coronavirus Chronicles — The Pain of Adaptation

Although for many people, physical exercise is an important part of their program to vanquish obesity, a contrary belief holds that exercisers tend to negate their extra physical activity by eating more. There is a study of Ecuadorian children that we will surely mention again, of which journalist Gretchen Reynolds wrote in The New York Times,

When children gain excess weight, the culprit is more likely to be eating too much than moving too little… The findings also raise provocative questions about the interplay of physical activity and metabolism and why exercise helps so little with weight loss, not only in children but the rest of us, too.

Disappointment with an effort that does not immediately produce an astonishing change can discourage people from pursuing change at all. Perhaps the best thing for people is to disconnect the idea of weight loss from the idea of exercise, and eliminate that mental link when arranging their daily routines.

This is especially important in a time when many Americans are constrained by circumstances from using the means and facilities they were accustomed to. Maybe the neighborhood gym only allows six people in at a time, or maybe the financial crisis of the pandemic closed it forever. According to The Wall Street Journal, gyms have been one of the hardest-hit industries. The cost of cleaning products alone is significant.

Formerly devoted customers have been forced to cut expenses, and neglected to renew their memberships. As a result, an estimated three million health club jobs have vanished. Huge companies, including the iconic Gold’s Gym, have gone bankrupt.

Belief systems clash

Financial pressure is not the only factor that makes things difficult. For adults, the conflict has encroached on what used to be one of the most ideology-free environments existing in the country. Now, some people refuse to work out in a face mask, while others will shun a gym that does not require masks.

Some wonder whether spacing the stationary bikes farther apart even helps to prevent the spread of aerosol droplets. Others are so eager, they will sneak into a closed gym with keys they previously had, or tell the press that even though they gave up restaurant dining and travel, a gym workout is the only “risk activity” they can’t abandon.

Businesses are willing to adapt and cater more to the at-home fitness buffs, which is lovely, except that the pandemic is also causing people to lose their homes. If the choice is between paying rent or buying a set of kettlebells, rent tends to win. Still, people who have equipment at home, and even those who are working with minimal environmental support, like a floor and a stairway, can buy streaming classes from their gyms or find guidance on YouTube for free.

And they may not be primarily seeking weight loss, but a whole spectrum of benefits that accrue from exercise, some of which undoubtedly connect indirectly with weight loss. It is not only a physical quest but a psychological one as well.

Your responses and feedback are welcome!

Source: “Exercise vs. Diet? What Children of the Amazon Can Teach Us About Weight Gain,” NYTimes.com, 02/24/21
Source: “Gyms Are Reopening, but Everything’s Different,” WSJ.com, 03/16/21
Image by Ms. Phoenix/CC BY 2.0

Coronavirus Chronicles — Keep It Moving

This page has spoken of Alasdair Wilkins, who lost 100 pounds by spending an hour each day walking an uphill treadmill while watching movies. One of his notable quotations is, “I was thinking about my weight loss on a very small scale: I just wanted to feel better…”

And this is why the question of physical exercise is so vital, no matter when. In what we tend to call “normal” times (although no times really are), people face limitations and barriers that keep them from experiencing a helpful amount of physical movement. The pandemic just happens to exaggerate the problem. More than ever, people need to feel better.

Stuck at home?

Take parents, for example. Sometimes it can be very stressful for parents to spend a lot of time around the children. Also, painful as it may be for grownups to acknowledge, children can find it quite stressful to spend too much time around their parents. Everybody needs to chill out, and strenuous physical exercise is a proven route to contented exhaustion. Habitual exercisers swear that it improves their moods.

When people are in better moods, they are easier to get along with, and also find others easier to tolerate. Even in the face of restricted access to venues specifically designed for exercise, it is possible to do enough movement to keep the blood and lymph circulating efficiently. Consider all the film and television drama scenes that show a prisoner staying fit within the limitations of a tiny cell. Kids and grownups can do that kind of thing at home. Stretching is good too, and can be accomplished in a very small space.

Saving our lives with our legs

For the benefit of their cardiovascular systems and bone density, children need an hour of movement each day, and most kids — eight out of 10 in Great Britain, for instance — don’t have that. Journalist Peter Walker writes in The Guardian,

If we don’t use our biggest muscles, notably in our legs, for long periods, there is a cellular effect that makes our bodies less good at breaking down certain fats, which can affect the way they process glucose.

Walker discusses the work of Harvard professor I-Min Lee, whose field of expertise is inactivity, and who teaches that “doing something is almost always better than nothing.” He references a recent study showing that taking 4,400 steps per day will actually keep an old woman alive longer than taking 2,400 steps per day.

Regular cyclists live longer, too. Even 10 minutes of exercise per day can be a life-changer. Walker writes,

And when you do start moving, the impact is immediate in effect, and astounding in extent. The US government guidelines on activity note that, on the same day you manage a single period of moderate-to-vigorous activity, you will see a reduction in blood pressure, better insulin sensitivity, improved sleep, fewer anxiety symptoms, and improved cognitive function.

Walker was told by expert Steve Blair that the best kind of activity to choose is “The one you’ll do and keep doing.” Which is exactly what mega-weight-loser Alasdair Wilkins told reporters who eagerly interviewed him. He tried the treadmill/movie combo, discovered that it wasn’t so bad, and realized that he wouldn’t mind doing it again tomorrow. No big deal.

Your responses and feedback are welcome!

Source: “‘Inactivity is an ongoing pandemic’: the life-saving impact of moving your body,” TheGuardian.com, 02/06/21
Image by Earl McGehee/CC BY 2.0

Coronavirus Chronicles — Assorted Parents and Their Ways

The paradigm of the cozy nuclear family, with mother and father and 2.2 children, is far from the norm. Especially in these perilous times, all kinds of relatives, friends, and acquaintances find themselves in motley households, out of necessity. But there are still many parent couples left, and what they need to do is buttress, and not undermine, each other. More than ever, parents need to cooperate, and that holds true whether they are together or apart.

Cohabiting parents

Parents are going crazy, at a time they most need to keep their heads. In parts of the country where circumstances are really rough, it’s all about day-to-day survival. In other places, food shortages have barely manifested, and the easiest thing to do is stay in, eat, sleep, consume media, and possibly even engage in a bit of substance misuse. Most of the outlets through which people let off steam and regain their emotional equilibrium are not available.

Being half of a partnership makes everything more fraught. Parents need to have private conversations and opportunities for other sorts of intimacy. If at all possible, they might find ways to give each other relief from child care, even when everyone is unavoidably together. If one parent can give the other even a half-hour break, that can be a blessing.

Of course, professional help from a therapist (virtual or otherwise) is very much to be desired, but even though online consultation with a professional is easier than ever, many factors keep people from taking advantage of the available opportunities.

Turn it up to 11

As if all that was not stressful enough, what about the former couples who have moved apart and moved on, but who share custody of a child, or children? Co-parenting can get incredibly messy. When kids move from one household to another, especially with an expanded cast of characters, things can become complicated.

Even at the best of times, divorced parents can tend to be careless about things like allergies, junk food, sleep schedules, and screen time. Often, they get up to real mischief, trying to outdo each other as the beneficent dispenser of treats. They might curry favor by neglecting to set boundaries or behavior standards. They might ridicule such ideas as serving vegetables or measuring food servings. Prompted by insecurity and hostility, they might expect the children to be little snitches.

In the pandemic scenario, indifferent parents might let the handwashing slide and the masks get lost. The kids mingle within the alternate household’s exclusive “bubble” which might — who knows? — comprise 100 people. Will they take the kids’ temperatures? Do they know the warning signs that should trigger serious concern?

Parents who share custody can’t be blamed for wondering, “Can I trust those people to keep the kids — and, by extension, me — safe from contagion? Or are they going to do something stupid, just to prove some goofy point?” Natasha Caleel wrote of people she knew,

There were parents who were using COVID-19 as leverage in custody battles, parents unable to take time off from essential jobs, parents losing their jobs altogether, or even worse, parents who were worried about matters such as neglect or abuse.

Nobody wants their child to get the virus, because of its intrinsic danger, and also because being sick is one of the gateways to meaningful obesity. Nobody wants their child to become obese, for all the reasons that existed before, and because the virus targets people who are carrying extra pounds. It’s an all-around raw deal.

Your responses and feedback are welcome!

Source: “My Ex And I Are Co-parenting Amid COVID-19, And It’s Full Of Unexpected Challenges,” HuffPost.com, 12/31/20
Image by spader/CC BY 2.0

Coronavirus Chronicles — Problems Not Readily Visible

Because of the pandemic disease itself and the inexorable reach of its influence and restrictions, people are a mess. We have depression, anxiety, grief, trauma, panic, agoraphobia, substance misuse, eating disorders, and PTSD.

In far too many lives, economic stress is a constant. Uncertainty takes a heavy toll, especially for people who are obliged to provide for others. Someone might be very confident about their own ability to “tough it out” during a bad patch, but when there are a partner and a child or five to be responsible for and worry about, the whole game changes.

People actively experiencing COVID-19 or recovering from it are, as we learned, susceptible to mental health disorders. And so, it turns out, are parents. The American Psychological Association recently issued a report on the mental and physical health of more than 3,000 parents whose under-18 children still live at home.

Nobody said it would be easy

Parents face two distinct sets of problems, their own and other people’s. Three-quarters of the adult subjects said they would have liked more emotional reinforcement than they got during 2020. No doubt, the same can be said of children. They too have felt deprived of emotional support. The hugely painful irony here is that the people who theoretically care about each other the most, are the very ones who cause the angst.

At any age, the people who are the most willing to help are sometimes the least able. And the ones who potentially are the most able to help, are not willing. Little kids, ideally, are able to brighten their parents’ lives, but too many children are asked to shoulder adult emotional burdens and compensate for what is missing in the adults’ relationship.

Where is obesity in this?

Everywhere. As we have seen, COVID-19 and the avoidance of it, and eating disorders, and mental health glitches, all exacerbate each other. Senior reporter Catherine Pearson writes in HuffPost,

55% of dads and 47% of moms say they’ve gained weight since the pandemic began, with an average of about 45 pounds for fathers and 27 pounds for mothers. Furthermore, just under half of dads in the survey said they were drinking more alcohol to cope with the pandemic, while about 30% of mothers said the same.

Many parents, needless to say, are not in the best frame of mind for putting their children’s chubby tummies at the top of the priority list. One of the oldest rules in the book is, “Pick your battles.” When parents are stressed about making sure the kids do their lessons and don’t bash each other’s brains in, snack policing might be the last thing on their minds. Remote learning is nobody’s idea of fun, as proven by the emotionally drained state of many parents who have to cope with it. Pearson writes,

Roughly half of mothers whose children are still learning at home reported their mental health has worsened since the pandemic began, while 30% of fathers whose children are still learning at home said the same.

Whether in the home or outside, a parent might feel the need to put a good face on it and pretend to love how the plague has given us the opportunity to spend so much time with the family. To keep up that kind of a facade is psychologically exhausting.

This era, the study authors say, will leave behind “lasting physical and psychological effects,” and no one yet has any idea how far from the end of it we are.

Your responses and feedback are welcome!

Source: “New Report Shows Just How Much American Parents Are Flailing Right Now,” HuffPost.com, 03/15/21
Image by waferboard/CC BY 2.0

Coronavirus Chronicles — Our Inner Workings and COVID-19

COVID-19 currently reigns over the globe, and the mental health aspects of that are all mixed up with concerns about obesity. The 236,379-subject study we mentioned found that coronavirus survivors do not always actually get over it, in the sense of returning to their pre-illness states of health and well-being. Instead, half a year later, about one-third of them suffer from neurological and mental health malfunctions.

Journalist Sarah Marsh sums up,

The most common diagnoses after Covid were anxiety disorders (occurring in 17% of patients), mood disorders (14%), substance misuse disorders (7%), and insomnia (5%)… After taking into account underlying health characteristics, such as age, sex, ethnicity and existing health conditions, there was a 44% greater risk of neurological and mental health diagnoses after Covid-19 than after flu.

Predictions say that primary and secondary care services are about to get slammed, prompting Dr. Jonathan Rogers, of University College London, to say:

Sadly, many of the disorders identified in this study tend to be chronic or recurrent, so we can anticipate that the impact of Covid-19 could be with us for many years.

Oxford University’s Prof Paul Harrison, the lead author of the aforementioned study, says:

Although the individual risks for most disorders are small, the effect across the whole population may be substantial for health and social care systems due to the scale of the pandemic and that many of these conditions are chronic.

So much for the “blood-brain barrier”

Scientists suspect that the action of SARS-CoV-2 on the brain can cause long-term neurological problems. For experimental purposes, they used stem cells to cultivate “organoids,” and turned the virus loose on them. No direct infection of neuronal cells was observed.

But the choroid plexus epithelial cells, which produce and secrete cerebrospinal fluid? That’s a different story. Those cells express ACE2, a cellular protein that COVID has a key to. So the choroid plexus layer can be infected by the virus, which proceeds to move in and reproduce itself. Even leaving neuronal cells out of it, explains Dr. Melanie Krause, it is alarming that the virus can damage the choroid plexus layer…

[…] because some proteins that usually make up the tight contacts between the cells were mislocalised. This caused brain-barrier leakage, which in humans could enable the entry of pathogens, immune cells and cytokines into cerebrospinal fluid and the brain, and potentially lead to neuroinflammation. This in turn could result in long-term neurological symptoms, such as chronic fatigue and memory loss.

The next step is to figure out whether the virus is able to spread through the body via the cerebrospinal fluid.

Your responses and feedback are welcome!

Source: “One in three survivors of severe Covid diagnosed with mental health condition,” TheGuardian.com, 04/07/21
Source: “Organoids indicate that SARS-CoV-2 damages the brain barrier,” BioNews.org, 10/26/20
Image by red, white and black eyes/CC BY 2.0

FAQs and Media Requests: Click here…

Profiles: Kids Struggling with Weight

Profiles: Kids Struggling with Obesity top bottom

The Book

OVERWEIGHT: What Kids Say explores the obesity problem from the often-overlooked perspective of children struggling with being overweight.

About Dr. Robert A. Pretlow

Dr. Robert A. Pretlow is a pediatrician and childhood obesity specialist. He has been researching and spreading awareness on the childhood obesity epidemic in the US for more than a decade.
You can contact Dr. Pretlow at:

Presentations

Dr. Pretlow’s invited presentation at the American Society of Animal Science 2020 Conference
What’s Causing Obesity in Companion Animals and What Can We Do About It

Dr. Pretlow’s invited presentation at the World Obesity Federation 2019 Conference:
Food/Eating Addiction and the Displacement Mechanism

Dr. Pretlow’s Multi-Center Clinical Trial Kick-off Speech 2018:
Obesity: Tackling the Root Cause

Dr. Pretlow’s 2017 Workshop on
Treatment of Obesity Using the Addiction Model

Dr. Pretlow’s invited presentation for
TEC and UNC 2016

Dr. Pretlow’s invited presentation at the 2015 Obesity Summit in London, UK.

Dr. Pretlow’s invited keynote at the 2014 European Childhood Obesity Group Congress in Salzburg, Austria.

Dr. Pretlow’s presentation at the 2013 European Congress on Obesity in Liverpool, UK.

Dr. Pretlow’s presentation at the 2011 International Conference on Childhood Obesity in Lisbon, Portugal.

Dr. Pretlow’s presentation at the 2010 Uniting Against Childhood Obesity Conference in Houston, TX.

Food & Health Resources